Determinants of health-related quality of life in a multinational systemic sclerosis inception cohort
February 1, 2018
Morrisroe K, Hudson M, Baron M, de Vries-Bouwstra J, Carreira P.E., Wuttge D.M., Wang M., Frech T.M., Stevens W., Proudman S.M., Nikpour M for the International Systemic Sclerosis Inception Cohort (INSYNC) collaboration
Systemic sclerosis (SSc) is a chronic multisystem autoimmune disease characterised by vasculopathy and excessive collagen production leading to skin and internal organ fibrosis (1). It is commonly classified into two distinct subtypes based on the degree of skin fibrosis, namely limited (lcSSc) and diffuse cutaneous (dcSSc) subsets.